StackIQ — Clinical Research

Independent summaries of clinical studies, reviews, and preprints covering supplements and adjacent health topics. Every summary names the study type and links to the original paper.

Featured research

Editor’s picks
ReviewPreliminary evidence

Can a Calming Supplement Really Help You Sleep?

A new sleep-nutrition review places L-theanine in the serious sleep-support conversation — but the strongest read is relaxation and wind-down support, not a guaranteed insomnia fix.

l-theaninesleepsleep qualityrelaxation+2
Meta-analysisStrong evidence

The Fiber Supplement That Actually Moved LDL in 41 Clinical Trials

A 2025 meta-analysis of 41 randomized trials found psyllium modestly lowered LDL and total cholesterol, with no clear effect on triglycerides or HDL.

psylliumcholesterolLDLtotal cholesterol+5
Meta-analysisStrong evidence

Ashwagandha for stress looks promising — but it’s not an instant calm button

People usually want to know whether ashwagandha meaningfully helps everyday stress, how fast it works, and whether the hype around cortisol is backed by actual trials.

ashwagandhastressanxietycortisol+4

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Search by supplement, health goal, or evidence strength.

Try “sleep,” “stress,” “LDL,” “ashwagandha,” or “creatine.”

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4 research summaries found
Observational studyPreliminary evidence

Can Low Vitamin D Affect Your Mood?

A large genetics study suggests vitamin D and depression may share underlying biology — making vitamin D status a smart marker to know, track, and correct when low.

vitamin Ddepressionmoodgenetics+2
ReviewPreliminary evidence

Can a Calming Supplement Really Help You Sleep?

A new sleep-nutrition review places L-theanine in the serious sleep-support conversation — but the strongest read is relaxation and wind-down support, not a guaranteed insomnia fix.

l-theaninesleepsleep qualityrelaxation+2
Meta-analysisStrong evidence

The Fiber Supplement That Actually Moved LDL in 41 Clinical Trials

A 2025 meta-analysis of 41 randomized trials found psyllium modestly lowered LDL and total cholesterol, with no clear effect on triglycerides or HDL.

psylliumcholesterolLDLtotal cholesterol+5
Meta-analysisStrong evidence

Ashwagandha for stress looks promising — but it’s not an instant calm button

People usually want to know whether ashwagandha meaningfully helps everyday stress, how fast it works, and whether the hype around cortisol is backed by actual trials.

ashwagandhastressanxietycortisol+4